Research Authors

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.5
USERS' SCORE
Good
Based on 10 Reviews
8.4
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Phosphatidylserine (PS) from Lecithin (Sunflower) (Helianthus annuus) Seed Oil
100 mg

Top Medical Research Studies

We evaluated the effects of phosphatidylserine (PS)-containing liposomes on high cholesterol and atherosclerosis. In our study with rabbits on a high-fat diet, we administered PS liposomes and found notable reductions in harmful cholesterol levels and plaque size compared to controls.

Both PS and atorvastatin-loaded PS liposomes effectively lowered LDL and total cholesterol without impacting other lipid levels. While we observed significant improvements in plaque characteristics and intima-media thickness, other factors like triglycerides and HDL remained unchanged.

Overall, PS liposomes appear promising for improving lipid profiles and aiding in plaque regression.
Read More
9
PSLs may reduce atherosclerosis risk
We explored the effects of phosphatidylserine liposomes (PSLs) on high cholesterol and its relation to atherosclerosis in a study featuring ApoE-/- mice. By introducing PSLs alongside a high-fat diet, we saw a significant reduction in atherosclerosis, with a 53% decrease in lesion size. This was attributed to an increase in protective B1a lymphocytes, leading to enhanced immune responses and lower inflammation levels. While promising, these findings suggest a potential therapeutic route rather than a guaranteed solution for cholesterol management in humans.
Read More
8
Phytosterol milk reduces LDL cholesterol
We explored how phytosterol (PhyS) and omega-3 (ω3) enriched milk can influence cholesterol levels in overweight individuals. In our study, 32 participants consumed either PhyS- or ω3-fortified milk for 28 days each.

Results showed that PhyS-milk significantly reduced LDL cholesterol levels more than ω3-milk and improved LDL's resistance to oxidation. While ω3-milk impacted triglycerides, PhyS-milk primarily altered LDL lipid composition.

Overall, both milk variants contributed to healthier LDL profiles, suggesting benefits beyond just lowering cholesterol and triglycerides.
Read More

Most Useful Reviews

7.5
Improved lipid profile
32 people found this helpful
Phosphatidylserine is a natural compound vital for cell membranes, facilitating nutrient transfer between cells. It supports brain health and the normal functioning of the nervous system, influencing learning, memory, and mood. I've been taking this supplement for two months, and my cholesterol levels have improved. Overall, my lipid profile is significantly better.
Read More
9
Resolved sleep issues
9 people found this helpful
I've struggled with sleep disturbances all my life. After reading that this product helps shut down the adrenal glands, I started taking 4-5 tablets before bedtime. Finally, my sleep issues, even unmanageable with high-dose melatonin, have improved significantly. I must reorder every 1.5 months, but the quality of the phosphatidylserine is excellent, and the sleep benefits are clear.
Read More
9
Vital health supplement
5 people found this helpful
Phosphatidylserine and phosphatidylcholine are key elements for cell function. They support brain activity and nutrient transport while helping eliminate excess cholesterol. As we age, this supplement is essential for maintaining cell health. This quality phosphatidylserine effectively provides multiple benefits.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.5
  • All Researches
We evaluated the effects of phosphatidylserine (PS)-containing liposomes on high cholesterol and atherosclerosis. In our study with rabbits on a high-fat diet, we administered PS liposomes and found notable reductions in harmful cholesterol levels and plaque size compared to controls.

Both PS and atorvastatin-loaded PS liposomes effectively lowered LDL and total cholesterol without impacting other lipid levels. While we observed significant improvements in plaque characteristics and intima-media thickness, other factors like triglycerides and HDL remained unchanged.

Overall, PS liposomes appear promising for improving lipid profiles and aiding in plaque regression.
Read More
9
PSLs may reduce atherosclerosis risk
We explored the effects of phosphatidylserine liposomes (PSLs) on high cholesterol and its relation to atherosclerosis in a study featuring ApoE-/- mice. By introducing PSLs alongside a high-fat diet, we saw a significant reduction in atherosclerosis, with a 53% decrease in lesion size. This was attributed to an increase in protective B1a lymphocytes, leading to enhanced immune responses and lower inflammation levels. While promising, these findings suggest a potential therapeutic route rather than a guaranteed solution for cholesterol management in humans.
Read More
8
Phytosterol milk reduces LDL cholesterol
We explored how phytosterol (PhyS) and omega-3 (ω3) enriched milk can influence cholesterol levels in overweight individuals. In our study, 32 participants consumed either PhyS- or ω3-fortified milk for 28 days each.

Results showed that PhyS-milk significantly reduced LDL cholesterol levels more than ω3-milk and improved LDL's resistance to oxidation. While ω3-milk impacted triglycerides, PhyS-milk primarily altered LDL lipid composition.

Overall, both milk variants contributed to healthier LDL profiles, suggesting benefits beyond just lowering cholesterol and triglycerides.
Read More
8
Atorvastatin normalizes platelet activation
We examined the impact of atorvastatin on platelet activation in patients with high cholesterol. In our study with 33 hypercholesterolemic patients and a control group of 40 healthy volunteers, we found that those with high cholesterol had increased platelet activation markers. Notably, atorvastatin treatment reduced this overactivity, correlating with lowered total and LDL cholesterol levels.

This indicates that atorvastatin may not only help manage cholesterol but also normalize platelet function, offering broader cardiovascular benefits.
Read More

User Reviews

USERS' SCORE
Good
Based on 10 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Improved lipid profile
32 people found this helpful
Phosphatidylserine is a natural compound vital for cell membranes, facilitating nutrient transfer between cells. It supports brain health and the normal functioning of the nervous system, influencing learning, memory, and mood. I've been taking this supplement for two months, and my cholesterol levels have improved. Overall, my lipid profile is significantly better.
Read More
9
Resolved sleep issues
9 people found this helpful
I've struggled with sleep disturbances all my life. After reading that this product helps shut down the adrenal glands, I started taking 4-5 tablets before bedtime. Finally, my sleep issues, even unmanageable with high-dose melatonin, have improved significantly. I must reorder every 1.5 months, but the quality of the phosphatidylserine is excellent, and the sleep benefits are clear.
Read More
9
Vital health supplement
5 people found this helpful
Phosphatidylserine and phosphatidylcholine are key elements for cell function. They support brain activity and nutrient transport while helping eliminate excess cholesterol. As we age, this supplement is essential for maintaining cell health. This quality phosphatidylserine effectively provides multiple benefits.
Read More
9
Normalised cholesterol
2 people found this helpful
When taken consistently, this supplement aids in normalising cholesterol levels!
Read More
9
Great cholesterol reduction
1 people found this helpful
This product effectively lowers cholesterol levels.
Read More

Frequently Asked Questions

7.5
Improved lipid profile
32 people found this helpful
Phosphatidylserine is a natural compound vital for cell membranes, facilitating nutrient transfer between cells. It supports brain health and the normal functioning of the nervous system, influencing learning, memory, and mood. I've been taking this supplement for two months, and my cholesterol levels have improved. Overall, my lipid profile is significantly better.
7.5
Cholesterol management
1 people found this helpful
Lecithin helps normalise fat metabolism, prescribed by my doctor to manage my cholesterol levels. I have taken it for two months, taking it in combination with a proper diet. My cholesterol, which was low, is now returning to normal, thanks to this supplement.
7.5
Effective treatment
1 people found this helpful
My doctor prescribed this drug to normalise fat metabolism. I take one capsule three times a day with meals. I've seen results; my cholesterol has decreased! 😊
9
Great cholesterol reduction
1 people found this helpful
This product effectively lowers cholesterol levels.
9
Normalised cholesterol
2 people found this helpful
When taken consistently, this supplement aids in normalising cholesterol levels!
9
Fat metabolism normalisation
1 people found this helpful
This excellent drug normalises fat metabolism. I take one drop three times a day with meals, and my cholesterol has dropped.
9
Resolved sleep issues
9 people found this helpful
I've struggled with sleep disturbances all my life. After reading that this product helps shut down the adrenal glands, I started taking 4-5 tablets before bedtime. Finally, my sleep issues, even unmanageable with high-dose melatonin, have improved significantly. I must reorder every 1.5 months, but the quality of the phosphatidylserine is excellent, and the sleep benefits are clear.
We evaluated the effects of phosphatidylserine (PS)-containing liposomes on high cholesterol and atherosclerosis. In our study with rabbits on a high-fat diet, we administered PS liposomes and found notable reductions in harmful cholesterol levels and plaque size compared to controls.

Both PS and atorvastatin-loaded PS liposomes effectively lowered LDL and total cholesterol without impacting other lipid levels. While we observed significant improvements in plaque characteristics and intima-media thickness, other factors like triglycerides and HDL remained unchanged.

Overall, PS liposomes appear promising for improving lipid profiles and aiding in plaque regression.
9
PSLs may reduce atherosclerosis risk
We explored the effects of phosphatidylserine liposomes (PSLs) on high cholesterol and its relation to atherosclerosis in a study featuring ApoE-/- mice. By introducing PSLs alongside a high-fat diet, we saw a significant reduction in atherosclerosis, with a 53% decrease in lesion size. This was attributed to an increase in protective B1a lymphocytes, leading to enhanced immune responses and lower inflammation levels. While promising, these findings suggest a potential therapeutic route rather than a guaranteed solution for cholesterol management in humans.
8
Phytosterol milk reduces LDL cholesterol
We explored how phytosterol (PhyS) and omega-3 (ω3) enriched milk can influence cholesterol levels in overweight individuals. In our study, 32 participants consumed either PhyS- or ω3-fortified milk for 28 days each.

Results showed that PhyS-milk significantly reduced LDL cholesterol levels more than ω3-milk and improved LDL's resistance to oxidation. While ω3-milk impacted triglycerides, PhyS-milk primarily altered LDL lipid composition.

Overall, both milk variants contributed to healthier LDL profiles, suggesting benefits beyond just lowering cholesterol and triglycerides.

References

  1. Naeini MB, Momtazi-Borojeni AA, Ganjali S, Kontush A, Jaafari MR, et al. Phosphatidylserine-containing liposomes: Therapeutic potentials against hypercholesterolemia and atherosclerosis. Eur J Pharmacol. 2021;908:174308. 10.1016/j.ejphar.2021.174308
  2. Padro T, Vilahur G, Sánchez-Hernández J, Hernández M, Antonijoan RM, et al. Lipidomic changes of LDL in overweight and moderately hypercholesterolemic subjects taking phytosterol- and omega-3-supplemented milk. J Lipid Res. 2015;56:1043. 10.1194/jlr.P052217
  3. Hosseini H, Li Y, Kanellakis P, Tay C, Cao A, et al. Phosphatidylserine liposomes mimic apoptotic cells to attenuate atherosclerosis by expanding polyreactive IgM producing B1a lymphocytes. Cardiovasc Res. 2015;106:443. 10.1093/cvr/cvv037
  4. Labiós M, Martínez M, Gabriel F, Guiral V, Martínez E, et al. Effect of atorvastatin upon platelet activation in hypercholesterolemia, evaluated by flow cytometry. Thromb Res. 2005;115:263.
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